In Antifolate Drugs in Cancer Therapy, Ann Jackman and a panel of highly regarded researchers comprehensively review the current status of novel antifolates, an important class of anticancer drugs.
Book Title: Antifolate Drugs in Cancer Therapy
Author:Ann L. Jackman
Published on 1999-01-22 by Springer Science & Business Media
ISBN: 9781592597253 / 1592597254
Total Page: 456
Book Category:Medical
Book is About: Cancer
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In Antifolate Drugs in Cancer Therapy, Ann Jackman and a panel of highly regarded researchers comprehensively review the current status of novel antifolates, an important class of anticancer drugs. The distinguished contributors discuss the preclinical and clinical pharmacology of methotrexate, other dihydrofolate reductase inhibitors, 5-fluorouracil, and the new generation of antifolates-the thymidylate synthase and glycinamide ribonucleotide formyltransferase inhibitors. In addition, they review in depth the modulation of antifolate drugs, folate and antifolate transport mechanisms, polyglutamation, resistance, and drug combinations, as well as pharmacogenomics, pharmacodynamics, regulation of gene expression, and mechanisms of cell death. The wide and progressive scope of Antifolate Drugs in Cancer Therapy provides entré to exciting new avenues for future research, and constitutes a new standard reference for all basic scientists and clinicians engaged in cancer therapeutics.
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- Antifolate Drugs in Cancer Therapy published by Springer Science & Business Media since 1999-01-22 with ISBNs. The book ISBN 13 Code is 9781592597253 and ISBN 10 Code is 1592597254
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- The book has "456 Pages" is Printed at BOOK underMedicalCategory
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